Adriana "Ana" Soria
Secret, known only to high-ranking American officials
Place of Birth
Spectacular Spider-Man Vol. 3 #15 (2004)
Recently, Ana surfaced in New York, still youthful and calling herself "The Queen". She demonstrated complete control over anyone possessing the so-called "insect gene," an atavistic DNA feature which connected some humans to the point where they split from insects on the evolutionary tree; Spider-Man among them. While her human drones built her a nest in a New York highrise, Ana chose Spider-Man as her mate. She forced a fateful kiss on the web-slinger that unleashed an enzyme into his body. When he resisted, she began executing civilians, then used her powers to immobilize him. Spider-Man was only saved when Captain America knocked Ana off the building. Surviving the fall, Ana moved her operations underground to a secret lab, where she had held the doctor responsible for her transformation since abducting him years before, and waited for the arrival of Spider-Man who was slowly mutating due to her kiss.
Initially growing extra eyes, extra arms and fangs, Spider-Man was drawn to and defeated by the Queen before completely morphing into a giant spider. Ana expected the spider to give birth to her offspring but once the transformation was complete the spider died instead. Distraught, Ana destroyed the lab and left without witnessing Peter Parker's rebirth from the spider's womb, with a few extra spider-like powers. Ana still held New York hostage, threatening to detonate a bomb that would exterminate all human life within 600 miles. Spider-Man disarmed the bomb and an unrelated explosion seemingly killed Ana.