Nuke was very strong for a normal human (above peak physical strength), and almost impervious to pain and conventional injury. He also possessed superhuman speed with peak range of 700 mph. The latter was due to his skin which had been reinforced with some sort of plastic.
Nuke was a savage fighter, and very good with a firearm.
Nuke used an enormous sub-machine gun nicknamed "Betsy" in his missions. Besides conventional machine gun ammunition, Betsy also held six light artillery rounds and two incendiary missiles. On Betsy's side Nuke used an LED counter to count the number of fatalities he had inflicted with his weapon. Nuke also had an unmarked military helicopter for air support, operated by an unnamed colonel.
Simpson took red pills (amphetamines) to boost his adrenaline in a fight, white (barbiturates) to bring him down and blue (sedatives) to keep him calm and relaxed. The red pills were revealed to be placebos. Nuke's adrenaline is raised when the keyword 'No V.C.' is chanted to him, which sends him into a fury since the word had been developped into a trigger word in Vietnam.