It's a super-team team-up as the Squad helps out the Fantastic Four with an ambush from the alien Skrulls and Super-Skrull. Meanwhile, Dr. Doom is making a devious deal with a mysterious cosmic villain named Thanos. As the battle rages in the Baxter Building and outer space, our heroes find that both threats are connected and they may have to make a deal of their own to save the Earth!

The FF return home from an extra-dimensional adventure to find the Baxter Building and everyone in it just a little bit off. Their usually-angry neighbors are suddenly all too happy to chat. They come bearing strange gifts, and oddly enough, seem extremely interested in the FF's powers. Soon it becomes obvious that the Baxter Building has been invaded by shape-shifting aliens - THE SKRULLS! But as the FF discover, whenever you deal with Skrulls, there's always more going on than meets the eye!

Susan forces the rest of the team to take part in 'Fantastic Fifth for a Day,' an attempt to drum up a little good PR for the team. But the contest is interrupted by the return of the SKRULLS. The FF aren't exactly worried by the awkward shape shifting aliens� that is, until they reveal the SUPER SKRULL�a genetically altered warrior who possesses all of the Fantastic Four's powers! And the team realizes they're in real trouble when they learn the Super Skrull has teamed up with Ronan the Accuser! The team's only hope might lie in the hands of the 'Fantastic Fifth�' a nerdy teenager named Rupert.

"Helping Hand, Iron Fist": Bruce Banner goes to Los Angeles to ask Tony Stark for help. Wanting to help his friend, Rick Jones follows Banner and finds himself in the middle of an earth-shattering battle between Iron Man and the Hulk. Will Iron Man and War Machine be able to cure Banner before Gabe Jones and his S.H.I.E.L.D. agents take down the Hulk?

"Man to Man, Beast to Beast": Bruce Banner travels to Canada to find his old friend, Dr. Walter Lankowski and try to get rid of the Hulk once and for all. But when Bruce finds his friend, a terrible secret is revealed!

Bruce befriends Mitch McCougthen who offers his help to find a cure for the gamma radiation responsible for turning Banner into the Hulk. But when their experiment goes wrong, McCoughten turns into Zzzax, a being of pure energy. Can the Hulk stop him before he destroys a dam?

"Innocent Blood": Ghost Rider comes to town, and he's tracking the Hulk! Simultaneously, Talbot is also looking for the Hulk and uses an infectious blaster on him. Now, the only way to save Banner's life is to make the Hulk madder than he's ever been before!

After escaping General Ross, the Hulk meets the Gamma Mutant Warriors and hides out at their base. While there, the Abomination kidnaps Banner and takes him to the Leader. Will Betty and Rick be able to save him before the Leader and Gargoyle find the key to his gamma mutation?

"Doomed": Bruce Banner travels to Washington D.C. to see his cousin, Jennifer Walters. The reunion is interrupted when Doctor Doom captures them, planning to use his mind control device on the Hulk. In the process, Jennifer is transfused with Bruce's blood and becomes the She-Hulk!

In this first episode of the series, Bruce Banner attempts to cure himself of the Hulk but his experiment is shut down by General Ross and Major Talbot. They capture the Hulk and take him to the Gamma Base, where Banner recalls his origin. Suddenly, the Abomination arrives on the scene, sent by the Leader and Gargoyle to capture Banner, and it's up to the Hulk to stop him.

The astonishing duo of Ant-Man and Wasp take you on a tour of the Big House, the world's smallest super villain prison.

Kang the Conqueror, the undisputed ruler of Earth in the 40th Century, has a problem. There is a disturbance in the time stream--his entire reality is being wiped from existence, and the entire disturbance has a single source: Captain America.

"Fantastic Fortitude": Banner and She-Hulk go to New York hoping to find Reed Richards and ask for help in finding a cure for the Hulk. However, the Fantastic Four is on vacation, except for the Thing! And when the Ogress and the Leader's Gamma Warriors decide to attack the trio, it's sure to be clobberin' time!

HYDRA's maniacal scheme to win World War II rages out of their control--and in the midst of the chaos, a chance for Captain America and Bucky to stop the Red Skull, once and for all!

In the heat of World War II, Captain America and Bucky mount a desperate assault against a top-secret HYDRA base in Norway. But things take a turn for the worst when they come face to face with Hydra’s own Super Soldier…the nefarious Red Skull.

It's the final episode! At a Mutant/Human Relations Summit, Henry Peter Gyrich attacks and severely injures Professor Xavier with an energy disruptor. Meanwhile Magneto makes final preparations to take over the world with his mutant army, but on the eve of the invasion Cyclops, Wolverine, and Jean Grey infiltrate Genosha to tell Magneto that Xavier is dying. Magneto halts his plants out of respect to his long-time friend and joins the X-Men as they say farewell to their beloved mentor.

The Hulk may be able to take on tanks, assault choppers, and heavy artillery, but what about two of S.H.I.E.L.D.’s most highly trained agents? Introducing…Hawkeye and the Black Widow!

The assault on Asgard was thwarted, but the mastermind behind the attack has yet to join the fray. Enter Loki, Thor’s most cunning foe…and his brother.

Banished to the Isle of Silence, Loki contemplates the events that lead him here. Did he truly lose the battle for Asgard, or have his sinister machinations only just begun?

"Mortal Bounds": Gargoyle releases a gamma virus on the citizens of Detroit, and Bruce Banner is the only one who can stop it from spreading. To make matters worse, Betty is infected with an extreme dosage of the virus! Bruce meets Doctor Donald Blake, who transforms into the mighty Thor. Together, they race to find a cure!

In London, England's Victorian era, two scientists, Dr. James Xavier and Dr. Nathaniel Essex, hotly debate Charles Darwin's theory of natural selection. Essex believes mutants are the next genetic step forward and begins a bizarre experiment involving mutant evolution. The origin of Mr. Sinister is revealed, as Dr. Xavier attempts to stop Essex before he goes too far.