In this first episode of the series, Bruce Banner attempts to cure himself of the Hulk but his experiment is shut down by General Ross and Major Talbot. They capture the Hulk and take him to the Gamma Base, where Banner recalls his origin. Suddenly, the Abomination arrives on the scene, sent by the Leader and Gargoyle to capture Banner, and it's up to the Hulk to stop him.

"They Call Me Mr. Fixit": A new super-villainess named Allure arrives in Chicago along with her enforcer Crusher Creel. But before she can take over the town she'll have to get through an even newer player in the Chicago underworld: She-Hulk and her right hand man, "Mr. Fixit"!

"And the Wind Cries...Wendigo!": After hearing about the existence of a creature resembling the Hulk, Betty Ross goes out to find it. What she finds is not the Hulk, but the legendary Wendigo!

"Fashion Warriors": She-Hulk agrees to be a model for a charity fashion show in Miami. But when the Leader and Gargoyle attack with their Gamma Warriors, She-Hulk must team up with Betty Ross and a trio of tough models to defeat the villains and avoid a fashion faux-pas!

"Darkness and Light" Part 1: Betty Ross and Doc Samson finish a Nutrient Bath that will separate Bruce Banner from the Hulk permanently. Rick Jones seeks the help of the Outcasts and manage to smuggle the Hulk onto the Gamma Base for the procedure.

"Hollywood Rocks": The Earth is threatened by falling Asteroids and the Hulk is the only one that can stop them! But when Doctor Doom emerges into the scene, things get a little more complicated. Meanwhile, She-Hulk is cast into to star in a Hollywood film!

"Darkness and Light" Part 2: Banner and the Hulk have been separated. Now suffering from amnesia and without Banner to control his rage, the Hulk goes on a murderous rampage. But things take an unusual turn when the Leader and Gargoyle capture the Hulk and transfer the Leader's intellect into the Hulk's body!

"Mission: Incredible": A parasite called the Hybrid takes over the body of General Ross! Meanwhile, Gray Hulk and She-Hulk team up with Agent Gabriel Jones and S.H.I.E.L.D. to save an unstable Gamma Power Core at the military installation known as Sea Base.

"Darkness and Light" Part 3: Bruce Banner is determined to stop the Hulk after they are separated. Equipped with exo-armor, he finds himself fighting the Hulk and realizes that neither of them can survive much longer separated. Faced with only one option left, Banner must find a way to reverse the Nutrient Bath and become one with the Hulk again!

"The Lost Village": When the Hulk rescues an elderly man, he is given a medallion that allows him to change back to Banner at will!

"Hulk of a Different Color": The Nutrient Bath experiment has turned Rick Jones into a new version of the Hulk and changed Bruce Banner into the Gray Hulk. After saving Thunderbolt Ross's life during a battle, Bruce Banner is instead charged with attempted murder! Luckily for Bruce, his cousin Jennifer Walters aka She-Hulk is one of the best lawyers in town!

"Down Memory Lane": Jennifer Walters returns home to attend her high school reunion and brings the Hulk along for the ride. Meanwhile, Gargoyle declares his love for her and the Leader and Abomination try to capture the Hulk. To make matters worse, Jennifer Walters finds out that she might become the She-Hulk permanently!

"Mind Over Anti-Matter": A dark entity travels to our dimension and is looking for a physical host to house its energy. Impressed with the size and strength of the Hulk, the entity sets its sights on the giant. She-Hulk must enlist the aide of Dr. Strange to go inside Banner's mind and rid him of the demon once and for all!

After escaping General Ross, the Hulk meets the Gamma Mutant Warriors and hides out at their base. While there, the Abomination kidnaps Banner and takes him to the Leader. Will Betty and Rick be able to save him before the Leader and Gargoyle find the key to his gamma mutation?

Bruce befriends Mitch McCougthen who offers his help to find a cure for the gamma radiation responsible for turning Banner into the Hulk. But when their experiment goes wrong, McCoughten turns into Zzzax, a being of pure energy. Can the Hulk stop him before he destroys a dam?

"Helping Hand, Iron Fist": Bruce Banner goes to Los Angeles to ask Tony Stark for help. Wanting to help his friend, Rick Jones follows Banner and finds himself in the middle of an earth-shattering battle between Iron Man and the Hulk. Will Iron Man and War Machine be able to cure Banner before Gabe Jones and his S.H.I.E.L.D. agents take down the Hulk?

"Man to Man, Beast to Beast": Bruce Banner travels to Canada to find his old friend, Dr. Walter Lankowski and try to get rid of the Hulk once and for all. But when Bruce finds his friend, a terrible secret is revealed!

"Innocent Blood": Ghost Rider comes to town, and he's tracking the Hulk! Simultaneously, Talbot is also looking for the Hulk and uses an infectious blaster on him. Now, the only way to save Banner's life is to make the Hulk madder than he's ever been before!

"Doomed": Bruce Banner travels to Washington D.C. to see his cousin, Jennifer Walters. The reunion is interrupted when Doctor Doom captures them, planning to use his mind control device on the Hulk. In the process, Jennifer is transfused with Bruce's blood and becomes the She-Hulk!

"Fantastic Fortitude": Banner and She-Hulk go to New York hoping to find Reed Richards and ask for help in finding a cure for the Hulk. However, the Fantastic Four is on vacation, except for the Thing! And when the Ogress and the Leader's Gamma Warriors decide to attack the trio, it's sure to be clobberin' time!

"Mortal Bounds": Gargoyle releases a gamma virus on the citizens of Detroit, and Bruce Banner is the only one who can stop it from spreading. To make matters worse, Betty is infected with an extreme dosage of the virus! Bruce meets Doctor Donald Blake, who transforms into the mighty Thor. Together, they race to find a cure!