Just as construction of the new Xavier Institute is completed, the beautiful Emma Frost shows up at the gate and bargains her way onto the team by locating the missing Professor X for them. Using Cerebro She is able to detect him on the mutant island of Genosha. Wolverine immediately launches a full rescue mission to recover their lost mentor, but infiltrating Genosha will mean going up against one of the the X-Men's most dangerous enemies�Magneto.

A year after a mysterious explosion destroyed the Xavier Institute and broke up the weary X-Men � an embittered WOLVERINE has lost himself on the open road, haunted by the unexplained fate of the missing Professor X and Jean Grey.

Communicating telepathically with Professor Xavier in the future, Wolverine learns that Africa is about to be wiped out � by Storm. The X-Men rush to Africa to find their friend, but the trouble has already begun. Possessed by a psychic entity known as The Shadow King, Storm now thinks her homeland is burning, and is using the full scope of her powers to douse the flames. Wolverine must act quickly if he's to prevent the destruction of an entire continent�but to stop Storm without hurting her, Wolverine will need to find a way to free her mind from Shadow King's clutches.

When Forge's new creation � a collar designed to inhibit mutant powers � is stolen by master thief-for-hire Gambit, Wolverine must track him down and recover it. But when he finds Gambit, he discovers that the collar has already been sold�to a buyer working for Senator Kelly. Now Wolverine and Gambit must team up in order to steal back the collar before it can be reverse engineered and used against mutants everywhere.

Cargo ships have a booming side business � ferrying desperate refugee mutants to the island of Genosha. But when Nightcrawler realizes the refugees are mistreated, he secretly boards one ship and teaches the captain and crew a lesson. It seems like he has the situation in hand until the ship is boarded� by pirates. These modern day marauders have made a practice of scuttling ships and abducting the mutants onboard. It's up to Nightcrawler to defeat the pirates and save the refugees in a battle on the high seas.

When the Hulk is spotted on a destructive rampage in the Canadian wilderness, Nick Fury, director of the organization known as S.H.I.E.L.D., blackmails Wolverine into taking the savage monster down� permanently. But as Wolverine confronts the Hulk, he begins to realize all is not as it seems�there is more than one monster on the loose in the wild. Now, as if a full-on fight with the Incredible Hulk wasn't bad enough, Wolverine has to deal with a pack of creatures more savage than him OR the Hulk� the Wendigo.

Xavier gives Wolverine and the X-Men a mission that goes against everything they believe. They must not only save the Brotherhood, but also deliver an innocent mutant into the hands of the MRD. And if they fail � half the world's mutants will be wiped out.That's because the Brotherhood has boldly snatched the perfect living weapon from the MRD prisons � Nitro, a mutant who causes huge energy detonations. The problem is, this tortured young man can't control his power�something he has in common with ROGUE, who hates the way the Brotherhood is using him. After using Nitro to destroy the MRD databanks, Quicksilver plans to deliver him to Magneto on Genosha. Unfortunately, they have no idea what they've gotten themselves into�Nitro's powers are beginning to overload, and the next time he goes off it could mean the end�

In the future, Sentinels capture Xavier and place him in a detention camp. But worse, they also take possession of the mutant tracking device, Cerebro. To get it back, Xavier must gather the help of other mutant prisoners, and with this new band of X-Men fight his way into the heart of the Sentinel stronghold. But once they're inside, they still need a way out...

Nighcrawler makes it to Genosha, where he's welcomed with open arms by Magneto, and Magneto's daughter, the Scarlet Witch. At first the island paradise seems to be the perfect haven for mutants, but Nightcrawler soon discovers that Genosha has a dark side. Now Nightcrawler must evade Magneto's mutant acolytes, and figure out a way to get a warning to Wolverine and the X-Men.

Logan is haunted by an eerie dream�a remnant of his fragmented memories. To get to the bottom of what happened to him, he enlists the help of Emma Frost. With her assistance, Logan is able to locate and return to the place that he keeps dreaming of. But he should never have returned, because now his past knows where to find him. That past takes the form of Sabretooth and the shadowy organization that Logan used to work for... Weapon X.

The brooding, heart-sick Scott Summers is so desperate to find the missing Jean Grey that when he spots Harpoon, an old enemy of the X-Men on the street, he goes berserk. Harpoon was an agent of the vile mutant geneticist known as Sinister�someone that Scott believes could be responsible for Jean's abduction. Now, based on nothing but his own suspicions, the out-of-control Cyclops forces his way up Sinister's ladder of command, one rung at a time. But the closer Cyclops gets to Sinister himself, the more danger he's in. Wolverine and the X-Men race to find him, but Cyclops is walking into a carefully laid trap. And it could already be too late.

"Night Of The Sentinels" Part 1 After being attacked by a group of robots known as the Sentinels, Jubilation Lee meets the X-Men, a group of super heroes aiming for peace between mutants and the rest of society.

"The Toad, The Witch, & The Wardrobe": While Wanda is in search of her father, Magneto, Toad steals Nightcrawler's holo-image inducer in attempt to alter his appearance and woo the Scarlet Witch.

"Self-Possessed": Rogue starts having trouble controlling her powers when all the abilities she's absorbed over the years begin to surface again. When she inadvertently absorbs Mystique's shape shifting abilities, Rogue begins to morph into the many mutants whose powers she's acquired, including the vicious Sabretooth. Now the X-Men have to defeat one of their own before Rogue does too much damage.

"X-Treme Measures": When the Morlocks create a new sports drink that's harmful to mutants, it finds its way into Spyke's hands at a Skateboarding Competition. To make matters worse, Spyke's powers are becoming more and more uncontrollable and his temper is following suit. Meanwhile Kitty learns to drive, horrifying her worried fellow mutants.

"Blind Alley": While the X-Men work to restore Xavier's Institute after its devastating destruction, Mystique manages to break free of her incarceration. She soon sets a plan in motion that leads Cyclops into a deadly trap.

"The Stuff of Villains": When the Brotherhood is expelled from school with nowhere else to go, Magneto sends Gambit to get them to join his side. Meanwhile, Wanda gets her brother Pietro arrested and Magneto sends Gambit and his new recruits to break his son out of jail.

"Mainstream": Now that the world knows about mutants, Professor Xavier urges the X-Men and the Brotherhood's return to school to convince their peers they pose no threat. However, the school's Principal Kelly has other plans for the student mutant population.

"The Stuff of Heroes": Storm and Beast step in front of the Senate and try to curb rampant anti-mutant racism. The X-Men fight have to stop Juggernaut, who was unleashed by Mystique and is threatening to destroy a dam.

"Day Of Recovery": The remaining X-Men and Brotherhood members go to Area 51 to save their captive members. However, when Cyclops traps the treacherous Mystique in Area 51 to blackmail her into saying where Professor X is, the squads split. The X-Men are now alone in a world which shuns them.

"Day Of Reckoning" Part Two: The X-Men are shocked when Professor X teams them up with the Brotherhood to stop them, but then, a shocking twist reveals that nothing was to be as it seemed to be.