'Marvel's Agents of S.H.I.E.L.D.': Season 3 Refresher

With "Marvel's Agents of S.H.I.E.L.D." Season 6 premiere quickly approaching on Friday, May 10 at 8|7c on ABC, let's take a quick trip to the very beginning with a refresher because these S.H.I.E.L.D. agents have come so far in such a short time.

Don't miss the following refreshers:

• Marvel's Agents of S.H.I.E.L.D. Season 1 Refresher
• Marvel's Agents of S.H.I.E.L.D. Season 2 Refresher

Good and bad Inhumans, a time jump into the future, a mission to space, and an undead Ward? A lot happened during Season 3 of “Marvel’s Agents of S.H.I.E.L.D.” Season 3, and here’s what you’re going to need to know heading into Season 6.

Remember those pills of fish oil at the end of Season 2? They’ve now created hundreds of new Inhumans around the world, and the agents are tasked with tracking them down. S.H.I.E.L.D. Director Phil Coulson has created a new program, called Caterpillars, which he hopes will create a special ops team of Inhumans—or Secret Warriors. However, it’s easier said than done because many times before the S.H.I.E.L.D. agents can reach the new Inhumans, they’re killed by a mysterious being. A new organization is created to try and hunt down the killer, the Advanced Threat Containment Unit (ATCU), which is led by Rosalind Price. Eventually, the ATCU and S.H.I.E.L.D. learn that the killer is an Inhuman named Lash who can transform into a human and travel around undetected.

Meanwhile, months have passed since the monolith swallowed Jemma Simmons whole, but Leo Fitz refuses to give up looking for her. Just about giving up all hope, Fitz starts begging the monolith to open the portal again, and he’s saved at the last second by Bobbi Morse who notices sand on Fitz’s cheek. He might not have traveled through the portal himself, but now we know that it does lead somewhere. Daisy Johnson, with her seismic abilities, is able to open the portal and Fitz goes in to retrieving Simmons.

Simmons reveals that she’s been on an alien planet named Maveth, and she wasn’t there alone. A stranded NASA astronaut named Will Daniels was also trapped there, and not only did they work together to survive but also started a relationship—which does not sit well with Fitz. But, he and Simmons are still a team, and he agrees to try and help her get back to Maveth and save Will.

Wondering what Ward is up to? Obviously, not good things. He has decided to rebuild HYDRA and seek revenge on S.H.I.E.L.D. for killing Agent 33, and recruits Werner von Strucker (the son of Wolfgang von Strucker from “Avengers: Age of Ultron”) to help him and actually sends von Strucker to kill Andrew Garner, Melinda May’s ex-husband who has lately been consulting for S.H.I.E.L.D.. Garner survives the attack, and May captures von Strucker who reveals that it’s actually Garner who’s the Inhuman Lash.

Coulson (who’s already a little wary of the ATCU...but has also started a relationship with Price) decides to send in some agents to investigate it, including Lincoln Campbell, who tried to completely leave S.H.I.E.L.D. and the Inhumans behind, but couldn’t deal with seeing Lash kill so many of his Inhuman friends. Daisy and Campbell start a relationship, and the group soon uncovers that former HYDRA member Gideon Mack has started to rebuild HYDRA, and is using the ATCU to do it.

HYDRA isn’t also what we all thought it was. The basis of HYDRA was actually founded on the worship of a powerful Inhuman with near-godlike capabilities, and where is this Inhuman now? He’s been transported to Maveth, via the monolith, where he’s been living for thousands of years. HYDRA is trying to bring this Inhuman back to Earth in hopes of finally achieving world domination. In order to stop Price from sharing what information she does have about ATCU and HYDRA, Ward kills her which sends Coulson into a tailspin. Ward then kidnaps Fitz and Simmons, and while trying to track him down, Ward and Fitz enter the portal to head to Maveth; Coulson jumps into the portal, too. With this, Alphonso "Mack" Mackenzie is made temporary Director of S.H.I.E.L.D.

On Maveth, Fitz and Ward find Will, and thanks to a sandstorm, Fitz and Will are able to escape. Things appear to be finally looking up when Fitz realizes that the Inhuman Hydra is now looking for has taken possession of Will’s body. Elsewhere, Coulson kills Ward. Coulson and Fitz then return back to Earth, as the S.H.I.E.L.D. agents there close the portal to Maveth. However, unbeknownst to them, this Dark Inhuman, Hive, has now taken possession of Ward’s body and followed them back to Earth, too. Malick then discovers who he believes at first to be Ward, and then realizes it’s Hive. Things are looking up for HYRDA once again.

Thinking things with HYDRA and the Dark Inhuman have calmed down, for the time being, the agents turn their attention to an Inhuman named Elena Rodriguez who can “yo-yo” and snap back and forth through locations.

Also, Glenn Talbot is made the head of ATCU as the organization moves to the forefront, pushing S.H.I.E.L.D. away. The agents believe that there’s a HYDRA mole in the ATCU, and it’s later discovered to be Talbot himself, who is trying to free his son who had been captured. Hunter and Morse, trying to help, end up in Russia and kill a General who also happens to be an Inhuman. Not wanting to start an international debate, it’s decided that Hunter and Morse will leave S.H.I.E.L.D., so their operations, and S.H.I.E.L.D. itself, are not exposed.

A group called the Watchdogs suddenly springs up, and their mission is to draw attention to and then eliminate all the Inhumans. They’ll become a nasty thorn in S.H.I.E.L.D.’s side going forward.

Garner, who had been on the run since it was revealed that he was Lash, suddenly turns up and surrenders. He knows he’s going to permanently become Lash, which deeply upsets May as she can no longer help him. Daisy is also given a precognitive vision that foreshadows someone’s death.

After finally being captured by S.H.I.E.L.D., Malick warns Coulson that Hive can infect the mind of Inhumans, and later Daisy finds out that she is infected herself. She leaves S.H.I.E.L.D., but before she does, she creates an earthquake to destroy the base. Fitz and Simmons try to track down a scientist named Holden Radcliffe who they believe might be able to help them stop Hive. But, Radcliffe has his own agenda, as he’s also trying to turn humans into Inhumans, but unfortunately manages to turn his test subjects into primitive Inhumans.

Something nice and happy finally happens, as Fitz and Simmons finally act on their feelings for one another! They also use their combined super-smart forces to try and work on an Inhuman cure, testing it out on Campbell. It, unfortunately, doesn’t work and the Sokovia Accords are put into effect shortly after this. Coulson and Talbot discuss what should be done with the Inhumans, with Coulson insisting their information needs to remain a secret.

Daisy, still infected with Hive, tries to return to him, but is stopped and saved by Garner. While he manages to save her—and Daisy returns back to S.H.I.E.L.D.— Garner is killed. Once back at S.H.I.E.L.D., the agents try to locate a warhead that Hive is planning to launch, which will drop the new pathogen that Radcliffe has been working on and turn humans into primitive Inhumans. Hive then steals a S.H.I.E.L.D. ship and takes Daisy with him to detonate the missile. This plan is thankfully thwarted and Coulson decides that the stolen ship should be sent into space to safely destroy it. Due to the vision she saw earlier about a death, Daisy believes she’s the one to do it. However, Campbell stops her and takes the ship into space, killing himself and Hive in the process.

Six months later, it’s revealed that Daisy has left S.H.I.E.L.D. after Campbell’s death and is now working under the moniker Quake. Coulson is no longer the director of S.H.I.E.L.D. On top of that, Radcliffe uploads his artificial intelligence AIDA into a Life Model Decoy — aka a robot that looks exactly like a human.

Watch the "Marvel's Agents of S.H.I.E.L.D." Season 6 premiere on Friday, May 10 at 8|7c on ABC, with new episodes every Friday! Stream new episodes the next day on Hulu, On Demand or ABC.com.

For more information on “Marvel’s Agents of S.H.I.E.L.D.,” visit ABC.com, follow @AgentsofSHIELD on Twitter, and like “Marvel’s Agents Of S.H.I.E.L.D.”on Facebook for all the latest news and updates.